RecruitingPhase 1Phase 2NCT06144671

GT201 Injection For The Treatment Of Advanced Solid Tumors

A Single-Arm Phase I/II Clinical Study of Autologous Tumor-Infiltrating Lymphocyte Injection (GT201) for The Treatment Of Advanced Solid Tumors


Sponsor

Grit Biotechnology

Enrollment

18 participants

Start Date

Sep 13, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Expected to complete 7 to 18 evaluable subjects (patients with advanced solid tumors),3 dose groups.A modified "3+3" dose-escalation design is utilized,This includes both accelerated dose escalation and traditional "3+3" dose escalation.The first dose group is accelerated titration,The first dose group is an accelerated titration of 1 to 6 evaluable subjects;The second and third dose groups are based on the traditional "3+3" dose-escalation principle,The second and third dose groups are based on the traditional "3+3" dose-escalation principle, with 3 to 6 evaluable subjects enrolled respectively.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called GT201 for people with solid tumor, adult. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGGT201

Autologous tumor infiltrating lymphocyte injection


Locations(4)

The fifth medical center of the General Hospital of the Chinese people's Liberation Army

Beijing, Beijing Municipality, China

Union Hospital Tongji Medical College Huazhong University Of Science And Technology

Wuhan, Hubei, China

Shandong Cancer Hospital

Jinan, Shandong, China

West China Hospital Sichuan University

Chengdu, Sichuan, China

View Full Details on ClinicalTrials.gov

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NCT06144671


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