Exploring the Impact of a Multi-modal Nutritional Intervention in Patients Undergoing Chemotherapy for Pancreatic Cancer (FEED Trial)

This trial (called the FEED Trial) is studying whether a multi-part nutrition program — including dietary changes, protein supplements, fish oil, and exercise guidance — can help preserve strength and body composition in people with pancreatic cancer who are receiving chemotherapy before surgery (called neoadjuvant chemotherapy). **You may be eligible if...** - You are 18 years or older - You have been newly diagnosed with pancreatic ductal adenocarcinoma (a type of pancreatic cancer) - Your treatment team has recommended neoadjuvant chemotherapy (FOLFIRINOX or Gemcitabine/Nab-Paclitaxel) before surgery - You have adequate grip strength and can tolerate a scan to assess body composition **You may NOT be eligible if...** - You cannot eat orally and need tube feeding or IV nutrition - You cannot eat fish or pork (due to allergy, intolerance, religion, or preference), as the study uses these foods - You have a blood clotting disorder or liver cirrhosis where fish oil supplementation would be unsafe - You have uncontrolled high blood pressure (above 180/110 mmHg) that prevents exercise - You have a muscle-wasting neurological condition (e.g., multiple sclerosis, muscular dystrophy) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.