RecruitingNCT06153563

Evaluation of the Elasticity of the Mitral Valve

Evaluation of the Elasticity of the Mitral Valve Chordae by Uniaxial Traction in the Context of Mitral Valve Regurgitation With a Comparison of the Results: Mitral Valve Prolapse vs Restriction of Mitral Valve Movement


Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Enrollment

30 participants

Start Date

Oct 18, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

There is no information in the literature on the mechanobiological characteristics of mitral valve chords in living humans. All examinations were carried out on tissues taken from animals, either from cadavers or from frozen human tissues. The objective is to determine mechanobiological and histological characteristics of the mitral valve chords in living humans, as well as to compare differences in elasticity in different groups (Group A: patients with mitral valve prolapse versus Group B: patients with restrictive ischemic mitral valve).


Eligibility

Min Age: 45 Years

Inclusion Criteria1

  • All patients programmed for mitral valve replacement who have more than 45 years old

Exclusion Criteria4

  • Patients with mitral calcification
  • Mitral valve rheumatic disease
  • Mitral valve infections
  • Redo surgery on the mitral valve

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Interventions

OTHERData collection on patient history and intraoperative results.

Data collection on patient history and intraoperative results.


Locations(1)

CHU Saint-Etienne

Saint-Etienne, France

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NCT06153563


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