RecruitingNot ApplicableNCT06161779

Submental Flap for the Reconstruction of Hypopharyngectomy

Sun Yat-sen Memorial Hospital, Sun Yat-sen University


Sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Enrollment

40 participants

Start Date

Feb 16, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this observational study is to assess the safety and efficacy of submental artery island flap (SMAIF) in the reconstruction of laryngeal and hypopharyngal defects after the surgical resection of hypopharyngeal cancer. The main questions it aims to answer are: * The survival of SMAIF and the recovery of laryngeal function. * The oncologic outcomes of SMAIF comparing with other reconstructions or radiotherapy. Participants will underwent partial laryngectomy and hypopharyngectomy and reconstruction of SMAIF. Postoperative adjuvant radiotherapy will be recommented when adverse pathologic features were noted.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates using tissue from the neck (submental flap) to reconstruct the throat and voice box area after surgery for hypopharyngeal cancer (cancer of the lower throat). Researchers want to know if this technique offers better outcomes compared to other reconstruction methods. **You may be eligible if...** - You are an adult with cancer of the lower throat (hypopharynx) requiring surgery - The tumor can be removed surgically - You are healthy enough to undergo the procedure **You may NOT be eligible if...** - Your cancer has spread to areas that make surgery impossible - You have had prior surgery or radiation that would prevent use of the neck tissue flap - You have serious medical conditions that make major surgery too risky Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSurgical reconstruction

submental artery island flap (SMAIF) for the reconstruction of laryngeal and hypopharyngal defects after the surgical resection of hypopharyngeal cancer


Locations(1)

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

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NCT06161779