RecruitingNCT06163131

The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility


Sponsor

Aarhus University Hospital

Enrollment

35 participants

Start Date

Nov 27, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the movement of the diaphram. The diaphragm is the muscle used for breathing between the chest and the stomach. Some of these patients can receive treatment with endobronchial valves, where one-ways are inserted into the bronchial system the let out some of the excess air, and thereby relieve breathlessness. The goal of this observational study is to investigate the effect of endobronchial valves on the mobility of the diaphragm in patients with chronic obstructive pulmonary disease. The main questions it aims to answer are: * If the movement of the diaphragm improves after treatment with endobronchial valves. * If there is a link between improvement of diaphragm function and improvement of symptoms, lung function and physical ability. * If ultrasound scan immediately after the treatment will predict which patients will benefit from the treatment. Participants will undergo ultrasound before, 1 day after and 90 days after the procedure, and lung function examinations from their already planned control visits will be collected.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Patients selected to receive treatment with endobronchial valves
  • Signed informed consent

Exclusion Criteria2

  • Neuromuscular disease interfering with diaphragm function
  • Pleural effusion at time of preoperative or 90-days postoperative ultrasound

Locations(1)

Aarhus University Hospital

Aarhus, Denmark

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NCT06163131


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