MRI Analysis and Degenerative Spine
Universidade Nova de Lisboa
200 participants
Jan 1, 2024
OBSERVATIONAL
Conditions
Summary
Analysis of MRI advanced techniques in degenerative spinal disease. The main questions it aims to answer are: * Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease * What are the image biomarkers affected by disease * How they evolve with disease progression and treatment
Eligibility
Inclusion Criteria5
- Age between 50 and 85 years
- Diagnosis of spinal disease by clinical and imagiological criteria
- More than 3 months duration of disease
- Ability to give consent
- Fluent portuguese speaker
Exclusion Criteria6
- Previous spine surgery
- Spinal instability
- Neurological disease that might interfere with walking
- Known orthopedic conditions that causes significant gait impairment
- Dementia or development disorder with cognitive impairment
- Inability to give consent
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Interventions
Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.
Locations(1)
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NCT06163300