RecruitingPhase 2NCT06164613

Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial

Use of Cinnamomum Verum Extract Versus Placebo for Induction of Labor and Reduction of Physiological Phase 2-3 of Labor. Double-blind Randomized Clinical Trial. CINNALAB TRIAL


Sponsor

Universidad Nacional Autonoma de Honduras

Enrollment

70 participants

Start Date

Dec 4, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the research protocol is to evaluate the effectiveness of Cinnamomum verum extract for the initiation of labor. Cinnamaldehyde ((E)-3-Phenylprop-2-enal) is an α, β unsaturated aromatic aldehyde, derived from cinnamon (Cinnamomum Verum oil) used as a flavoring; It is a clear yellowish liquid substance, with a strong odor and flavor. It is the main component of cinnamon (63%), giving it its physicochemical properties. Cinnamon has been an element of empirical use for the beginning of labor, however, its effectiveness has not been demonstrated. Cinnamon has been reported for its ethnopharmacological properties in pregnancy, being used to facilitate childbirth, as a lactagogue and for postpartum recovery. In Honduras, its use has been reported to relieve nausea and vomiting during pregnancy, to reduce abdominal pain. , reduction of lower limb edema, to relieve anxiety during labor, as well as a lactagogue without convergent opinions.


Eligibility

Sex: FEMALEMin Age: 14 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Cinnamomum Verum oil extract and a drug called Placebo for people with first birth and labor onset and length abnormalities. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCinnamomum Verum oil extract

one capsule of 1000 mg orally of Cinnamomum Verum oil extract per day for 21-28 days

DRUGPlacebo

400 mg PO Canola oil soft gel capsule


Locations(1)

Hospital Escuela

Tegucigalpa, Francisco Morazán Department, Honduras

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NCT06164613


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