RecruitingNot ApplicableNCT06165302

Exercise in Prostate Cancer

EPC Trial: Exercise in Prostate Cancer


Sponsor

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Enrollment

20 participants

Start Date

Oct 16, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn how exercise intervention affects circulating tumor cells (CTC) in men with advanced prostate cancer. The primary objective is to determine if an exercise intervention decreases CTCs in men with advanced prostate cancer. Participants will have baseline screening assessments, followed by 12 weeks of exercise intervention, and then follow-up assessments 12 weeks after the end of the exercise intervention.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a structured exercise program — supervised aerobic and resistance training — can improve physical fitness, reduce fatigue, and improve quality of life in men with prostate cancer who are receiving androgen deprivation therapy (hormone treatment that reduces testosterone). This hormone therapy commonly causes muscle loss and fatigue. **You may be eligible if...** - You are a man diagnosed with prostate cancer (any stage) - You are currently receiving or about to start androgen deprivation therapy (ADT/hormone therapy) - You are able to exercise safely **You may NOT be eligible if...** - You have bone metastases in areas that make exercise unsafe (risk of fracture) - You have uncontrolled heart or lung disease - You recently had surgery and are still recovering - You have physical limitations that prevent participation in the exercise program Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALExercise Intervention

12 weeks of prescribed exercise intervention.


Locations(1)

Johns Hopkins University

Baltimore, Maryland, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06165302


Related Trials