RecruitingNCT06167174

Exploring Biomarkers for Therapeutic Response of Lupus Nephritis Based on Multi Omics Analysis

Exploring Biomarkers for Therapeutic Response of Lupus Nephritis Based on Multi Omics

Sponsor

Chinese SLE Treatment And Research Group

Enrollment

100 participants

Start Date

Dec 5, 2023

Study Type

OBSERVATIONAL

Conditions

Lupus Nephritis

Summary

This is an observational study of patients with lupus nephritis aiming to find biomarkers that can predict patients' response to immunosuppressants. We planed to collect 100 lupus nephritis patients' peripheral blood,kidney tissues and urine before and after treatment (mycophenolate mofetil or cyclophosphamide, in combination with glucocorticoids). Then multi omics analysis, including single cell RNA-seq, ATAC-seq and CITE-seq, will be performed to find new biomarkers for patients' response and prognosis.

Eligibility

Min Age: 16 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with lupus nephritis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 16 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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