RecruitingNot ApplicableNCT06168266

Effects of Eccentric Exercise Training in Patients With COPD

Effects of Smart Eccentric Exercise Training on Lymphocyte Immunity and Erythrocyte Rheology in Patients With Chronic Obstructive Pulmonary Disease

Sponsor

Fu Jen Catholic University

Enrollment

170 participants

Start Date

Dec 13, 2023

Study Type

INTERVENTIONAL

Conditions

COPD

Summary

The goal of this study is to design eccentric exercise strategies for COPD patients to comprehensively improve their cardiopulmonary/muscular fitness, immune and hemorheological functions, and quality of life, thereby improving the prognosis of their disease.

Eligibility

Min Age: 20 YearsMax Age: 80 Years

Inclusion Criteria5

Having undergone pulmonary rehabilitation for more than 3 months
Sign the written informed consent form
FEV1/FVC \< 0.70
Approval for exercise training granted by a specialist physician's assessment
Specialist physician's approval for exercise training

Exclusion Criteria14

Existing of tracheostomy
Those who use oxygen therapy or ventilator at home
Severe heart failure (NYHA III-IV)
Neuromuscular disease
Acute exacerbation within the past three months
Those who are unable to cooperate with the cardiopulmonary exercise test
Taking anticoagulant medications
Other conditions restricting exercise for over a year
Recent or planned significant cardiovascular surgery or intervention
Current or planned pregnancy within the next year
Planned heart transplant within the next six months
Heart failure due to uncorrectable valvular heart disease, congenital heart disease or obstructive cardiomyopathy
Inadequate ICD settings for exercise heart rate
Other exercise contraindications: unstable angina, uncontrolled blood pressure, orthostatic hypotension with symptoms, severe aortic stenosis, acute discomfort or fever, uncontrolled arrhythmias, uncompensated heart failure, acute pericarditis or myocarditis, recent thrombosis or thrombophlebitis, resting ST-segment deviation, uncontrolled diabetes, etc.