RecruitingNot ApplicableNCT06169605

Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study

Sponsor

Cairo University

Enrollment

20 participants

Start Date

Apr 1, 2024

Study Type

INTERVENTIONAL

Conditions

Tongue Neoplasms

Summary

Regarding oral cavity cancer, the high incidence of neck metastasis along with its impact on survival and prognosis are in favor of elective neck dissection. Moreover, occult metastases could develop at lower levels in the neck (levels IV-V) Regarding the tongue, the rate of skip (occult) metastasis involving unremoved level IV cervical lymph nodes in squamous cell carcinoma of the tongue ranges from 0 % - 11.4 %. However, no data is available or a correlation between the risk of level IV involvement and the affection of specific tongue subsites or a certain cutoff value of tumor thickness.

Eligibility

Min Age: 15 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how the thickness of tongue or floor-of-mouth cancers and their exact location relate to the spread of cancer to level IV lymph nodes (lymph nodes deep in the lower neck). The goal is to help surgeons decide when these lower lymph nodes need to be removed. **You may be eligible if...** - You have squamous cell carcinoma (a common type of cancer) of the tongue or the floor of the mouth - You are between 15 and 60 years old - Any gender is welcome **You may NOT be eligible if...** - Your cancer has come back after previous treatment (recurrent) - You have already received radiation therapy or chemotherapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREremoval of primary tumor, neck dissection

removal of the primary tumor with safety margins and removal of the neck lymph node levels I, II, III and IV. histological assessment of tumor thickness and whether it is associated with positive nodes in level IV or not.

Locations(1)

Faculty of Dentistry, Cairo University

Cairo, Egypt

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NCT06169605

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