Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study
Cairo University
20 participants
Apr 1, 2024
INTERVENTIONAL
Conditions
Summary
Regarding oral cavity cancer, the high incidence of neck metastasis along with its impact on survival and prognosis are in favor of elective neck dissection. Moreover, occult metastases could develop at lower levels in the neck (levels IV-V) Regarding the tongue, the rate of skip (occult) metastasis involving unremoved level IV cervical lymph nodes in squamous cell carcinoma of the tongue ranges from 0 % - 11.4 %. However, no data is available or a correlation between the risk of level IV involvement and the affection of specific tongue subsites or a certain cutoff value of tumor thickness.
Eligibility
Inclusion Criteria3
- Patients with squamous cell carcinoma of the tongue and floor of the mouth.
- Age group: from 15 to 60 years old
- No sex predilection
Exclusion Criteria2
- Patients with recurrent squamous cell carcinoma of the tongue and floor of the mouth.
- Irradiated patients or those taking chemotherapy.
Interventions
removal of the primary tumor with safety margins and removal of the neck lymph node levels I, II, III and IV. histological assessment of tumor thickness and whether it is associated with positive nodes in level IV or not.
Locations(1)
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NCT06169605