Niraparib Rechallenge After Surgery in Ovarian Cancer Patients With Oligometastatic Progression

This study looks at whether women with ovarian cancer that has come back in only a few spots (called oligometastatic progression) can benefit from surgery to remove those spots followed by restarting niraparib — a maintenance pill that was used previously. It examines whether this approach can delay further cancer spread. **You may be eligible if...** - You are a woman 18 or older with high-grade ovarian, fallopian tube, or peritoneal cancer - You previously received niraparib as maintenance therapy and your cancer responded - Your cancer has now come back in only a limited number of spots that can be surgically removed - You are in good health (ECOG performance status 0-1) with a life expectancy over 16 weeks **You may NOT be eligible if...** - Your cancer has spread widely and cannot be surgically removed - You have had prior surgical treatment for recurrent disease - You have certain serious health conditions or poor organ function - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.