Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

This study is looking for inherited genetic mutations in people diagnosed with lung adenocarcinoma (a specific type of lung cancer) who may have a family history of the disease. Many people may not know they carry inherited gene changes that increase cancer risk. The study aims to identify these mutations to better understand and potentially screen families. **You may be eligible if...** - You are 16 years or older with a confirmed diagnosis of lung adenocarcinoma - You have a family history of lung cancer (a first-degree relative with lung cancer, or two or more second-degree relatives), OR - You are a never-smoker or light smoker with lung adenocarcinoma, OR - Your cancer has a specific mutation (e.g., EGFR, ALK, ROS1) even without a family history - You have signed informed consent **You may NOT be eligible if...** - You do not have a confirmed pathological diagnosis of lung adenocarcinoma - Your life expectancy is less than 8 weeks - You have declined genetic testing Talk to your doctor to see if this trial is right for you.