Testosterone-induced Muscle Memory and Underlying Mechanisms
Long-term Effects of Anabolic Androgenic Steroids on Muscle Growth Potential: Testosterone-induced Muscle Memory and Underlying Mechanisms
Morten Hostrup, PhD
30 participants
Apr 1, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this project is to investigate underlying mechanisms of testosterone- and resistance training-induced muscle hypertrophy and muscle memory in humans.
Eligibility
Inclusion Criteria2
- Healthy men and women
- BMI of <26 and normal ECG and blood pressure
Exclusion Criteria6
- Smoking
- Chronic disease,
- Use of prescription medication
- Pain due to current or previous musculoskeletal injury
- Resistance training more than once per week in the 12 months leading up to the intervention
- Current or previous use of prohibited anabolic substances
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Interventions
Following testosterone/placebo injection, participants undergo supervised resistance training for 4 weeks. This period is followed by a washout period with no drug and either continued resistance training or detraining for 16 weeks. Thereafter, another 4-week period with supervised resistance training is commenced, with no drug.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06188767