RecruitingNot ApplicableNCT06191159

Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions

A Randomized Controlled Trial Comparing the Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions


Sponsor

University of British Columbia

Enrollment

186 participants

Start Date

Dec 9, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without immediate breast reconstruction. It is hypothesized that there will be no significant difference in mastectomy scar cosmesis. The purpose and objectives of this study are: 1. To evaluate and compare the cosmetic scar result from the use of scalpel, standard electrocautery, or PEAK PlasmaBlade for initial incision for total mastectomy procedures without immediate breast reconstruction. 2. To inform future equipment choices for breast surgery including potential elimination of scalpels and their attendant risks.


Eligibility

Inclusion Criteria1

  • Patients having a total mastectomy with or without axilla surgical staging

Exclusion Criteria7

  • Patients having immediate breast reconstruction
  • Patients with a diagnosis of inflammatory breast cancer
  • History of keloid scar formation
  • History of connective tissue disorder (scleroderma or rheumatoid arthritis with skin involvement)
  • Patients with prior incision at the planned mastectomy site.
  • Patients with known suture hypersensitivity
  • Patients with evidence of current infection

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Interventions

DEVICEScalpel and standard electrocautery or PEAK PlasmaBlade

Scalpel followed by completion of surgery with standard electrocautery or PEAK PlasmaBlade.

DEVICEPEAK PlasmaBlade

PEAK PlasmaBlade for entire surgery.

DEVICEStandard Electrocautery

Standard Electrocautery for entire surgery.


Locations(1)

Mount Saint Joseph Hospital

Vancouver, British Columbia, Canada

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NCT06191159


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