RecruitingNot ApplicableNCT06191900

Clinical Study of GT201 in the Treatment of Advanced Gynecological Tumors (advanced Cervical Cancer)

Single Arm Clinical Study of Autologous Tumor Infiltrating Lymphocyte Injection (GT201) in the Treatment of Advanced Gynecological Tumors (advanced Cervical Cancer)


Sponsor

Grit Biotechnology

Enrollment

26 participants

Start Date

Jun 5, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study is an early exploration clinical study with one arm. The study consists of two stages, namely the dose escalation stage and the dose extension stage:


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing GT201, a personalized immune cell therapy made from your own tumor-fighting cells (tumor-infiltrating lymphocytes or TILs), for women with advanced cervical cancer that has not responded to standard treatments. **You may be eligible if...** - You have advanced cervical cancer that has spread or cannot be treated with standard therapy - You have at least one tumor that can be safely removed and used to prepare your personalized cell therapy - You meet general health and organ function requirements **You may NOT be eligible if...** - You have an active autoimmune disease or need immune-suppressing drugs (like high-dose steroids) - You have had a blood clot, stroke, or serious clotting event within the last 3 months - You have active, uncontrolled infections (including HIV, hepatitis B, or hepatitis C) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALAutologous tumor infiltrating lymphocyte injection(GT201)

GT201 treatment for advanced gynecological tumors (advanced cervical cancer)


Locations(1)

Shanghai Tenth People's Hospital

Shanghai, Shanghai Municipality, China

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NCT06191900


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