Prognostic Value of Conization and Negative HPV After Conization in AIS and Early Stage Cervical Cancer

This study examines whether removing abnormal cervical tissue (a procedure called conization) combined with testing negative for HPV (human papillomavirus) afterward can predict good outcomes in women with early-stage cervical cancer. It also studies which HPV types are present before and after the procedure. **You may be eligible if...** - You are between 18 and 85 years old - You have been diagnosed with early-stage cervical cancer (Stage IB2 or adenocarcinoma in situ) - You are willing to have HPV testing before and after your conization procedure **You may NOT be eligible if...** - You are pregnant - You are under 18 years old - You have declined to continue in the study - Data on your HPV types, final pathology, or surgical complications is unavailable Talk to your doctor to see if this trial is right for you.