RecruitingNot ApplicableNCT06198400

Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion.

Indocyanine Green Fluorescence in Evaluation of Post-resection Pancreatic Remnant Perfusion After Pancreaticoduodenectomy


Sponsor

Charles University, Czech Republic

Enrollment

60 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Main goal of this study is to evaluate the blood flow in a post resection pancreatic remnant after pancreaticoduodenectomy with use of indocyanine green fluorescence. If the hypothesis will be proven, evaluation of perfusion of the pancreatic remnant with indocyanine green could be used to estimate the increased risk of the development of pancreatic fistula.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • All consecutive patients undergoing open pancreaticoduodenectomy at our department in the selected period

Exclusion Criteria3

  • Allergy to indocyanine green
  • Refusal by the patient
  • Mini-invasive procedure.

Interventions

DIAGNOSTIC_TESTPerioperative assessment of the perfusion of post-resection pancreatic remnant using indocyanine green-VerDye

The adequacy of the vascular supply of the post resection pancreatic remnant after pancreatic neck division will be evaluated using ICG detector. Indocyanine green fluorescence product -Verdye™ will be intravenously applied. The application of the substance will be performed according to the current consensus statement and recommendation


Locations(1)

Department of Surgery, Second Faculty of Medicine of Charles University and Military University Hospital Prague, Czech Republic

Prague, Czech Republic, Czechia

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NCT06198400


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