RecruitingNot ApplicableNCT06198400

Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion.

Indocyanine Green Fluorescence in Evaluation of Post-resection Pancreatic Remnant Perfusion After Pancreaticoduodenectomy


Sponsor

Charles University, Czech Republic

Enrollment

60 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Main goal of this study is to evaluate the blood flow in a post resection pancreatic remnant after pancreaticoduodenectomy with use of indocyanine green fluorescence. If the hypothesis will be proven, evaluation of perfusion of the pancreatic remnant with indocyanine green could be used to estimate the increased risk of the development of pancreatic fistula.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates the use of a special fluorescent dye called indocyanine green (ICG) to help surgeons better see and preserve healthy pancreatic tissue during a major surgery called pancreaticoduodenectomy (Whipple procedure). The dye glows under special light, helping the surgeon identify blood flow and tissue borders. **You may be eligible if...** - You are scheduled for open pancreaticoduodenectomy (Whipple surgery) at the study hospital **You may NOT be eligible if...** - You have an allergy to indocyanine green - You refuse to participate - You are undergoing a minimally invasive (laparoscopic or robotic) procedure instead of open surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTPerioperative assessment of the perfusion of post-resection pancreatic remnant using indocyanine green-VerDye

The adequacy of the vascular supply of the post resection pancreatic remnant after pancreatic neck division will be evaluated using ICG detector. Indocyanine green fluorescence product -Verdye™ will be intravenously applied. The application of the substance will be performed according to the current consensus statement and recommendation


Locations(1)

Department of Surgery, Second Faculty of Medicine of Charles University and Military University Hospital Prague, Czech Republic

Prague, Czech Republic, Czechia

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NCT06198400


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