RecruitingNCT06199258

Heterogeneity of Lung Ventilation Determined by EIT During PFT in Patients With PRISM

Heterogeneity of Lung Ventilation Determined by Electrical Impedance Tomography During Pulmonary Function Testing in Patients With Preserved Ratio Impaired Spirometry

Sponsor

Sir Run Run Shaw Hospital

Enrollment

200 participants

Start Date

Dec 5, 2023

Study Type

OBSERVATIONAL

Conditions

COPD

Summary

To evaluate the demographic characteristics of PRISm population in patients with pulmonary function tests recommended by outpatient physicians. To investigate whether EIT can identify spatial and temporal heterogeneity of lung ventilation in individuals with PRISm during pulmonary function testing. To investigate the distribution patterns of lung ventilation in individuals with PRISm using this technique, and provide references and evidence for early screening, diagnosis, treatment monitoring, and prognostic evaluation.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria2

Age ≥18 years old. Patients who need to complete lung function tests assessed by outpatient physicians.
Patients willing to participate in the study and sign an informed consent form.

Exclusion Criteria5

Patients with a history of lung diseases other than COPD, previous lung surgery, or radiation therapy.
Patients who cannot be evaluated for EIT or who interfere with EIT results, such as implanted pacemakers/cardioverters.
Patients who cannot complete EIT or may interfere with EIT results, such as those with implanted pacemakers/defibrillators.
Patients who cannot complete lung function tests, such as myocardial infarction or shock in the past 3 months; severe heart failure or angina in the past 4 weeks，uncontrolled hypertension (systolic \>200mmHg, diastolic \>100mmHg)，severe hyperthyroidism etc.
Vulnerable populations, including patients with mental illnesses, cognitive impairments, critically ill patients, illiterate, pregnant women, etc.