Radiologic Pathologic Correlation of Imaging to Distinguish True Progression From Pseudoprogression in Brain Malignancies

This study compares what brain MRI scans show with what the tumor actually looks like under the microscope in adults with brain tumors (gliomas). This helps researchers understand how well MRI scans can distinguish between true tumor growth, treatment-related changes, and scar tissue. **You may be eligible if...** - You are over 18 years old - You have had prior treatment for a brain tumor - You have a new or suspicious finding on a brain scan that may require further diagnosis - You are willing to attend all study visits and evaluations **You may NOT be eligible if...** - You are under 18 (pediatric brain tumors have a different profile and are excluded) - You are unwilling or unable to complete required visits Talk to your doctor to see if this trial is right for you.