Atrial Fibrillation (AF) Ablation to Prevent Disease Progression of AF-induced Atrial Cardiomyopathy in Women and Men
University Medical Center Groningen
604 participants
Jul 25, 2024
INTERVENTIONAL
Conditions
Summary
The goal of clinical trial is to compare AF ablation to pharmacological rhythm management (being rate or rhythm control) in AF patients with signs of atrial cardiomyopathy (as defined by left atrial volume index \>34 ml/m2) The main objective it aims to answer is to determine whether AF ablation compared to pharmacological rhythm management in ACMP patients with AF reduces the incidence of the composite primary endpoint of CV death and first CV hospitalization/urgent visit.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Pulmonary vein isolation using pulsed field ablation (PFA), cryoballoon or radiofrequency ablation (RFA)
1st line: rate control, 2nd line: pharmacological rhythm management. 3rd line: AF ablation
Locations(1)
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NCT06200311