RecruitingEarly Phase 1NCT06207552

Evaluation of the Safety, Tolerability and Efficacy of a Gene Therapy Drug for the Treatment of Pediatric Fabry Disease

A Single-arm, Open Label, Single-dose Clinical Study to Evaluate the Safety, Tolerability and Efficacy of BBM-F101 Injection in the Treatment of Pediatric Fabry Disease


Sponsor

Children's Hospital of Fudan University

Enrollment

6 participants

Start Date

Feb 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single-arm, open label, single-dose clinical study to evaluate the safety, tolerability and efficacy of BBM-F101 injection in the pediatric Fabry disease participants up to 52 weeks after infusion, and the long-term safety and efficacy of BBM-F101 injection up to 5 years after infusion. BBM-F101 injection is an adeno-associated virus (AAV) gene therapy product for the treatment of pediatric Fabry disease.


Eligibility

Min Age: 7 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying BBM-F101 injection for people with fabry disease. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICBBM-F101 injection

The dose of BBM-F101 injection will be calculated according to the participant's weight with single intravenous infusion.


Locations(1)

Children's Hospital of Fudan University

Shanghai, China

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NCT06207552


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