RecruitingNot ApplicableNCT06208202

Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study

The ICE Study: Perceptions of E-Cigarettes and Synthetic Cooling Agents (R01)


Sponsor

Ohio State University Comprehensive Cancer Center

Enrollment

300 participants

Start Date

May 8, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.


Eligibility

Min Age: 21 YearsMax Age: 29 Years

Inclusion Criteria4

  • Aged 21-29 years
  • Current e-cigarette (EC) user (defined as ≥ weekly use over the past 3 months)
  • Willing to provide informed consent and abstain from using their EC at least 12 hours prior to the four lab sessions
  • Read and speak English

Exclusion Criteria7

  • Recently COVID-19+ (defined as positive test in the past 30 days) or a recent COVID-19 hospitalization (defined as a hospitalization within the past 6 months)
  • Unstable or significant psychiatric conditions (past and stable conditions will be allowed)
  • History of cardiac event or distress within the past 3 months
  • Are currently pregnant, planning to become pregnant, or breastfeeding (will be verified with urine pregnancy test)
  • Have suffered from any serious lung disease or infection (e.g. , tuberculosis, cystic fibrosis, or lung cancer) in the past 30 days
  • Have hemophilia or another type of bleeding disorder
  • Are blind, severely visually impaired, deaf, hard of hearing, or have a severe motor disability

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Interventions

BEHAVIORALBehavioral Intervention

Receive and use flavored e-cigarettes (EC) as directed

OTHERBiospecimen Collection

Undergo biosample sample collection

OTHERSurvey Administration

Complete surveys


Locations(1)

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States

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NCT06208202


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