A Study of HLX42 in Advanced/Metastatic Solid Tumors
A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX42 (Anti-EGFR ADC) in Patients With Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech
102 participants
Mar 14, 2024
INTERVENTIONAL
Conditions
Summary
This study is an open-label first-in-human phase I clinical study to evaluate the safety and tolerability of HLX42.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
HLX42 is an anti-EGFR monoclonal antibody conjugated with a novel high potency DNA topoisomerase I (topo I) inhibitor, with a drug-antibody-ratio (DAR) of 8.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06210815