RecruitingNCT06212635

Hemostasis in Liver Cirrhosis and Hepatocellular Cancer

Novel Biomarkers for Evaluation of Hemostasis and Inflammation in Liver Cirrhosis


Sponsor

Region Stockholm

Enrollment

100 participants

Start Date

Dec 2, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Evaluating hemostasis in decompensated liver cirrhosis with novel hemostatic assays.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how blood clotting and bleeding processes work differently in people with advanced liver disease (cirrhosis) and liver cancer compared to healthy individuals. Cirrhosis changes how the liver makes clotting proteins, and researchers want to better understand these changes to improve care. Participants will have blood samples taken — no experimental treatment is given. **You may be eligible if...** - You are 18 or older - You have decompensated liver cirrhosis (advanced liver scarring with complications) - OR you are a healthy volunteer aged 18 or older willing to serve as a comparison **You may NOT be eligible if...** - You have had another type of cancer (outside the liver) in the past year - You have a blood clotting disorder not related to your liver disease - You have a blood disease such as leukemia, abnormal platelet counts, or hemoglobin disorders - You have had a previous liver transplant - You have received a blood transfusion in the last 7 days - You take blood thinners or antiplatelet medications (other than a preventive low-dose blood thinner) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTT-TAS

Blood test, laboratory assays


Locations(1)

Karolinska University Hospital

Stockholm, Huddinge, Sweden

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NCT06212635