RecruitingNCT06212635

Hemostasis in Liver Cirrhosis and Hepatocellular Cancer

Novel Biomarkers for Evaluation of Hemostasis and Inflammation in Liver Cirrhosis


Sponsor

Region Stockholm

Enrollment

100 participants

Start Date

Dec 2, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Evaluating hemostasis in decompensated liver cirrhosis with novel hemostatic assays.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patients with decompensated liver cirrhosis
  • years or older.
  • Healthy individuals 18 years or older will serve as controls.

Exclusion Criteria6

  • • Extrahepatic malignancy or recurrence of such within the last year.
  • Diagnosis of non-cirrhotic coagulopathy, coagulation disorder or thrombophilia prior to inclusion.
  • Diagnosis of hematological disease such as hematologic malignancies, non-cirrhotic thrombocytopenia or thrombocytosis, Polycytemia Vera, hemoglobinopathies
  • Previous liver transplantation.
  • Transfusions the last 7 days.
  • Treatment with platelet inhibitors or anticoagulant except for prophylactic dosage of LMWH. If a prophylactic dose of LMWH has been used study sampling with addition of antiFXa must be taken \>12 hours after the last injection.

Interventions

DIAGNOSTIC_TESTT-TAS

Blood test, laboratory assays


Locations(1)

Karolinska University Hospital

Stockholm, Huddinge, Sweden

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NCT06212635