RecruitingNot ApplicableNCT06220526

Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis

A Prospective Randomized Clinical Trial Comparing Menghini-type Needle and Franseen-type Needle for Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Pathological Diagnosis of Sarcoidosis


Sponsor

University Health Network, Toronto

Enrollment

128 participants

Start Date

Aug 18, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved sample quality for pathological diagnosis compared to the conventional Menghini-type needle.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Any adult patient aged 18 years or older with enlarged mediastinal and/or hilar lymph nodes
  • (≥10 mm short-axis diameter on a CT scan), suspected as having sarcoidosis based on clinical
  • history, physical exam, and other investigations, and booked for EBUS-TBNA.

Exclusion Criteria4

  • Patients that are unable to provide informed consent
  • \- Patients with lymphadenopathy strongly suspected to be secondary to other diseases based on
  • clinical history, physical exam, and/or other investigations (e.g., lung cancer, lymphoma,
  • infection).

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Interventions

DEVICEendobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)

Transbronchial biopsy with Menghini-type or Franseen type Needle


Locations(1)

Toronto General Hospital

Toronto, Ontario, Canada

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NCT06220526