Biomarkers Research in Anxiety for Validation and Efficacy

This trial is studying biological markers (biomarkers) — including brain activity, heart rate, and skin electrical signals — in young children aged 3 to 7 who have both autism spectrum disorder (ASD) and anxiety, to better understand how anxiety works in this population and whether a specific therapy (Being Brave) is effective and can be tracked biologically. **You may be eligible if...** - Your child is aged 3 years to 6 years 11 months - Your child has a confirmed diagnosis of both autism spectrum disorder and an anxiety disorder (per DSM-5) - Your child uses at least 2–3 word phrases when speaking - Your child has an IQ (verbal or non-verbal) above 80 - You (the parent/guardian) are English-speaking, willing to participate in the parent training component, and able to support homework activities **You may NOT be eligible if...** - Your child has a seizure disorder - Your child was born prematurely (before 36 weeks) or had a low birth weight - Your child has a known genetic condition (e.g., Fragile X syndrome) or neurological injury - Your child has previously received cognitive behavioral therapy (CBT) for anxiety - Your child has severe ADHD or oppositional behavior that would interfere with treatment - You as a parent are not fluent in English or English is spoken less than half the time at home Talk to your doctor to see if this trial is right for you.