RecruitingNot ApplicableNCT06223529

Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study

The Neural Mechanisms of Music Intervention for Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study


Sponsor

Anglia Ruskin University

Enrollment

5 participants

Start Date

Jul 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aims of the study are to recruit five participants with stroke upper limb hemiparesis and determine the effects on neural reorganisation of a three-week music intervention using electroencephalogram measures. Secondly, the researchers will measure for changes in arm function before and after the three-week music intervention. This is a single-arm pre-/post experiment Primary research questions: What are the neuroplastic changes induced by Therapeutic Instrumental Music Performance (TIMP)? Secondary research questions What are the functional changes in hemiparetic arm and hand induced by TIMP? Participants will be recruited once they have completed their statutory community stroke rehabilitation. They will receive 15 X music therapy sessions in their home over three-weeks. Exercises will be delivered by trained clinicians, including music therapists and stroke rehabilitations specialists. Exercises will be facilitated for full range of arm movement, using a range of percussion instruments on stands and handheld, and iPad with touchscreen instruments, which include keyboards and string instruments that can be played using pinch-grip, holding a stylus/plectrum. Pre-/post intervention period EEG recordings will made. Stroke Specific Quality of Life (SSQoL), Action Research Arm Test and nine-hole-peg-test data will be collected from participants in their homes at weeks: 1, 4, 7 and 10.


Eligibility

Min Age: 18 YearsMax Age: 110 Years

Inclusion Criteria6

  • Aged 18+
  • Ischemic stroke
  • Three weeks to 60 months post-stroke
  • 12 to 49/57 Action Research Arm Test (ARAT) score *
  • Able to follow instructions and consent
  • Right-hand dominant

Exclusion Criteria8

  • Hemorrhagic stroke
  • No movement in arm
  • Unable to move thumb and one finger. Loss of sensation and proprioceptive impairment will not lead to exclusion.
  • Unable to consent to participate
  • Currently receiving music therapy
  • Left-hand dominant
  • Ambidextrous
  • Not registered with a GP. We will require GP details to inform them in case of any incidental findings in the EEG.

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Interventions

BEHAVIORALTherapeutic Instrumental Music Performance

Exercises using musical instruments to improve hemiparetic hand and arm function


Locations(1)

Cambridgeshire COmmunity Services NHS Trust

Bedford, Bedfordshire, United Kingdom

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NCT06223529


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