Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis
Combining Transcranial Direct Current Stimulation and Yoga for Improved Pain Management for Knee Osteoarthritis: A Pilot and Feasibility Trial
McMaster University
68 participants
Oct 20, 2024
INTERVENTIONAL
Conditions
Summary
People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to complex nervous system changes, making current treatments, like exercise, not very successful. To address this, researchers suggest a new approach combining two things: a brain stimulation technique called Transcranial Direct Current Stimulation (tDCS) and yoga. TDCS helps with pain by changing how the brain works, and yoga, a safe practice, focuses on overall well-being. Together, the investigators aim to improve how the nervous system works from top to bottom. The research project wants to change how the arthritis pain is being managed by focusing on how it works. The investigators plan to test this combo in a study comparing real tDCS plus yoga with fake tDCS plus yoga. The investigators will look not only at pain but also at other measures related to pain and how the nervous system works. This new mix could be a meaningful way to reduce pain for people with knee arthritis.
Eligibility
Inclusion Criteria5
- community dwelling adults from Sherbrooke, Quebec, Hamilton and London, Ontario fulfilling the NICE criteria for KOA
- ≥45 years of age
- Diagnosis of Knee osteoarthritis OR
- Having movement-related joint pain with either no morning knee stiffness or stiffness of 30 minutes or less AND
- Experiencing an average pain intensity of ≥3 /10 in the past month
Exclusion Criteria15
- Systemic inflammatory arthritis.
- Any knee injection in the past 3 months.
- Inability to independently get up and down from the floor.
- Lower limb trauma or surgery within the last 6 months.
- Current participation in another OA clinical trial.
- Use of mobility aids.
- Currently receiving care for KOA pain (e.g., physiotherapy).
- Planned absences exceeding 1 week.
- Contraindications to transcranial direct current stimulation (tDCS) such as neurological or neuropsychiatric conditions.
- History of brain surgery or tumor.
- Metallic implants.
- Epilepsy or history of substance abuse or dependence.
- Cochlear or ocular implant.
- Presence of a pacemaker or cardiac defibrillator.
- Eczema on the scalp.
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Interventions
Yoga program: In weeks 2-9, participants will attend twice weekly 1-hour sessions of yoga led by a certified yoga instructor trained in the intervention by collaborator Pearson. Videos will be provided for completion of home sessions. The yoga program is based on the Pain Care Aware certification program.38 Details of the program as well as the training of instructors are provided in the appendices. Briefly, classes will consist of 3 parts: centring and warming up aimed at regulating physiology prior to beginning the yoga postures; yoga postures and guided relaxation.
Locations(3)
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NCT06228573