Autofluorescence in Surgery for Primary Hyperparathyroidism
Use of Intraoperative Autofluorescence Imaging in Surgery for Primary Hyperparathyroidism - a Randomized Controlled Trial.
Aarhus University Hospital
100 participants
Jan 1, 2024
INTERVENTIONAL
Conditions
Summary
The study aims to test if autofluorescence imaging (AF) is a useful surgical aid during parathyroidectomy (PTX) for primary hyperthyroidism (PHPT).
Eligibility
Inclusion Criteria3
- Age\>18 years and able to give informed consent.
- A diagnosis of PHPT.
- Planned exploratory PTX with ioPTH measurement.
Exclusion Criteria6
- Concordant high-confidence imaging; planned focused/selective PTX
- Previous thyroid or parathyroid surgery.
- Planned simultaneous thyroid surgery.
- MEN, lithium induced hyperparathyroidism.
- eGFR \< 30.
- Kidney transplant.
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Interventions
In the experimental group, the surgeon will use the EleVision IR camera system (Medtronic, USA) to visualize PTGs during surgery. The surgical field will be visualized with AF as a minimum of two times during surgery on each side of the neck: First upon exposing the undersurface of the thyroid gland, and secondly before removal of a pathological PTG. Also, removed PTGs will be examined ex vivo to document AF pattern.
Locations(1)
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NCT06230380