RecruitingNot ApplicableNCT06230549

Adaptive Radiotherapy in Patients With Gynecological Tumors

Prospective Randomized Validation of Adaptive Radiotherapy in Patients With Gynecological Tumors and Indication for Radiotherapy

Sponsor

University Hospital, Essen

Enrollment

30 participants

Start Date

Jan 15, 2024

Study Type

INTERVENTIONAL

Conditions

Radiation Cervical Carcinoma Adaptive Radiotherapy Gynecological Tumor Curative Treatment Optimization Adaptive Radiation Therapy Image Guided Radiotherapy

Summary

Prospective randomized evaluation of adaptive radiotherapy in the definitive radiotherapy of locally advanced gynecologic carcinoma (e.g. cervical carcinoma, endometrial carcinoma, vaginal carcinoma), in the postoperative situation or first series of external beam radiotherapy and in patients in whom radical surgery or HDR brachytherapy as dose boost is not an option.

Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria1

ECOG 0-1 confirmation by histophatology MR of the pelvis staging

Exclusion Criteria1

Recurrent disease Prior Radiotherapy in pelvic region stage pM1 or cM1

Interventions

RADIATIONAdaptive Radiotherapy

Adaptive Radiotherapy, online onboard adaptation of dose distribution with a specialist radiation oncologist and a medical physicist

Locations(1)

Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West

Essen, Germany / NRW, Germany

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NCT06230549

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