RecruitingNot ApplicableNCT06230549

Adaptive Radiotherapy in Patients With Gynecological Tumors

Prospective Randomized Validation of Adaptive Radiotherapy in Patients With Gynecological Tumors and Indication for Radiotherapy

Sponsor

University Hospital, Essen

Enrollment

30 participants

Start Date

Jan 15, 2024

Study Type

INTERVENTIONAL

Conditions

Radiation Cervical Carcinoma Adaptive Radiotherapy Gynecological Tumor Curative Treatment Optimization Adaptive Radiation Therapy Image Guided Radiotherapy

Summary

Prospective randomized evaluation of adaptive radiotherapy in the definitive radiotherapy of locally advanced gynecologic carcinoma (e.g. cervical carcinoma, endometrial carcinoma, vaginal carcinoma), in the postoperative situation or first series of external beam radiotherapy and in patients in whom radical surgery or HDR brachytherapy as dose boost is not an option.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying adaptive radiotherapy — a type of radiation treatment that is regularly adjusted based on how the tumor changes during the treatment course — for women with gynecological cancers (such as cervical or endometrial cancer). **You may be eligible if...** - You have a confirmed gynecological tumor (such as cervical or uterine cancer) - Your cancer has been confirmed by pathology - You are in good physical condition (ECOG 0-1) - You have had MRI staging of your pelvis - Your cancer has not spread to distant sites **You may NOT be eligible if...** - Your cancer has already come back after prior treatment (recurrent disease) - You have previously had radiation to the pelvic area - Your cancer has spread to distant organs (stage M1) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONAdaptive Radiotherapy

Adaptive Radiotherapy, online onboard adaptation of dose distribution with a specialist radiation oncologist and a medical physicist

Locations(1)

Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West

Essen, Germany / NRW, Germany

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NCT06230549

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