Speech Pattern Evaluation and Analysis for Knowledge of AD
Connected Language and Speech Along the Spectrum of ADRD: Digital Assessment and Monitoring
University of Wisconsin, Madison
165 participants
Jan 22, 2025
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease. Participants will complete speech collection sessions and a survey at home using an iPad. Participants can expect to be in the study for 3 years.
Eligibility
Inclusion Criteria5
- Must be enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) Clinical Core or IMPACT studies, or in the Wisconsin Registry for Alzheimer's Prevention (WRAP)
- Cognitively unimpaired or have a diagnosis of Mild Cognitive Impairment (MCI)
- Ages 40-80 years
- Completion of a W-ADRC or WRAP study visit within the past or upcoming 12 months
- Have provided W-ADRC or WRAP with blood plasma Alzheimer's Disease
Exclusion Criteria5
- Not actively enrolled in W-ADRC or WRAP
- Diagnosis of dementia
- Impaired capacity or unwilling to consent
- Major neurological conditions
- Speech disorders
Interventions
Participants will be asked to complete the speech collection procedures remotely/at home once per week for 8 weeks. The 8-week period of weekly remote speech collection will take place yearly for a total of 3 years. At the end of each 8-week study period for years 1-3, participants will complete a survey that asks questions about how easy/difficult the application was to use, how frustrated they felt using the application, and other usability questions.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06230783