RecruitingNCT06230783

Speech Pattern Evaluation and Analysis for Knowledge of AD

Connected Language and Speech Along the Spectrum of ADRD: Digital Assessment and Monitoring


Sponsor

University of Wisconsin, Madison

Enrollment

165 participants

Start Date

Jan 22, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease. Participants will complete speech collection sessions and a survey at home using an iPad. Participants can expect to be in the study for 3 years.


Eligibility

Min Age: 40 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is analyzing speech patterns — such as subtle changes in how people talk — to see whether these changes can detect early signs of Alzheimer's disease before cognitive symptoms become obvious. Participants complete voice recordings as part of their usual research study visit. **You may be eligible if...** - You are already enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) or WRAP study - You are cognitively unimpaired or have mild cognitive impairment (MCI) — not full dementia - You are between 40 and 80 years old - You have had a study visit within the past or upcoming 12 months - Blood plasma Alzheimer's markers have been collected as part of your existing enrollment **You may NOT be eligible if...** - You are not currently enrolled in W-ADRC or WRAP - You have a diagnosis of dementia - You have a major neurological condition or speech disorder - You are unable or unwilling to consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTalkTracker

Participants will be asked to complete the speech collection procedures remotely/at home once per week for 8 weeks. The 8-week period of weekly remote speech collection will take place yearly for a total of 3 years. At the end of each 8-week study period for years 1-3, participants will complete a survey that asks questions about how easy/difficult the application was to use, how frustrated they felt using the application, and other usability questions.


Locations(1)

University of Wisconsin

Madison, Wisconsin, United States

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NCT06230783