RecruitingNot ApplicableNCT06232122

Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer

Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer With CA125 Elevation From Complete Response After Therapy


Sponsor

Chang Gung Memorial Hospital

Enrollment

45 participants

Start Date

Aug 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

A prospective cohort imaging study in a single institution to evaluate 68Ga- FAPI-46 and 18F-FDG PET/CT imaging for detecting recurrent tumor lesions in patients of ovarian cancer with CA125 elevation from complete response after therapy


Eligibility

Sex: FEMALEMin Age: 30 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating two types of PET/CT scans — one using a tracer called 68Ga-FAPI-46 and the standard 18F-FDG scan — to see which is better at detecting ovarian cancer that has come back after successful treatment. **You may be eligible if...** - You have been diagnosed with ovarian cancer and had a complete response to treatment - You are between 30 and 80 years old - Your CA-125 blood marker (a sign of ovarian cancer) has risen above normal or doubled - You are willing to have further treatment if cancer is found again **You may NOT be eligible if...** - You have had another type of cancer - You are pregnant or breastfeeding - Your blood sugar is above 200 mg/dL while fasting - You are allergic to the scan contrast agents used - You are unable to lie still for 30 minutes during the scan Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TEST68Ga-FAPI-46

Intravenous injection of one dosage of 2 mCi 68Ga-FAPI-46

DIAGNOSTIC_TEST18F-FDG

Intravenous injection of one dosage of 5-10mCi 18F-FDG


Locations(1)

Chang-Gung Memorial Hospital, Linkou Branch

Taoyuan City, Taiwan

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NCT06232122


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