RecruitingNot ApplicableNCT06232304

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

Transforming Behavioral Healthcare to Improve the Quality of Life for Individuals With Childhood-onset Lupus


Sponsor

Michigan State University

Enrollment

175 participants

Start Date

Sep 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate the feasibility and effectiveness of a cognitive behavioral coping skills program, Treatment and Education Approach for Childhood-onset Lupus (TEACH), for youth with cSLE when integrated into medical care. This TEACH program aims to teach participants skills in order to cope with fatigue, pain, and depressive symptoms--symptoms that commonly affect adolescents and young adults with lupus.


Eligibility

Min Age: 12 YearsMax Age: 22 Years

Inclusion Criteria5

  • \) be diagnosed with cSLE, meeting the revised American College of Rheumatology Classification Criteria for SLE by age 18 years
  • \) be between the ages of 12 and 22 years
  • \) in recognition of the heterogeneity of cSLE symptoms, have elevations in fatigue (i.e., T scores ≥60; or at least moderate symptoms, on the PROMIS measure) OR depressive symptoms (≥5 on the PHQ-9, T Score ≥ 60 on the BDI or CDI II ), OR pain (i.e., average pain ≥3 out of 10 on the Pain VAS)
  • \) have English language proficiency (their primary caregiver can have English or Spanish language proficiency for the child to enroll)
  • \) those under age 18 years (US), or 16 years (Canada) must have a consenting caregiver

Exclusion Criteria3

  • \) other chronic medical conditions (e.g., juvenile arthritis)
  • \) a documented developmental delay, severe cognitive impairment, or thought disorder
  • \) an untreated major psychiatric illness (e.g., bipolar disorder, psychosis, severe depression (PHQ9 score ≥21, BDI/CDI II \> 90) or active suicidal ideation (SI), based on the Pediatric Health Questionnaire (PHQ-9) items plus clinical interview; see Measures section)

Interventions

BEHAVIORALTEACH

TEACH is a cognitive behavioral coping skills program. It consists of six one-hour weekly sessions that are conducted either in-person or remotely.


Locations(7)

University of Alabama Birmingham Hospital

Birmingham, Alabama, United States

Children's Hospital of New Orleans/ Tulane University

New Orleans, Louisiana, United States

Helen Devos Children's Hospital

Grand Rapids, Michigan, United States

Montefiore Medical Center

The Bronx, New York, United States

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

Seattle Children's Hospital

Seattle, Washington, United States

The Hospital for Sick Children

Toronto, Ontario, Canada

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NCT06232304