Menthol, Inflammation, and Nicotine Transition Study

This study looks at whether menthol cigarettes — the kind with a minty flavor — affect inflammation in the body more than regular cigarettes, which could raise the risk of heart disease. Participants who smoke menthol cigarettes daily will switch to non-menthol (but otherwise identical) cigarettes for four weeks, and researchers will measure changes in blood markers of inflammation. Adults aged 21–85 who currently smoke at least 5 menthol cigarettes per day and have done so for at least one year may be eligible. Participation involves blood draws, a smartphone-based app to track mood and cravings, and study-provided cigarettes. This summary was generated with AI assistance and is intended to help patients understand the study in plain language.