RecruitingNot ApplicableNCT06241482

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

A Randomized Controlled Clinical Study on Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care Patients


Sponsor

Shanghai 6th People's Hospital

Enrollment

80 participants

Start Date

Oct 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Enhanced recovery after surgery (ERAS) is a strategy of perioperative management aimed to accelerate the rehabilitation of patients through various optimized perioperative managements as well as ongoing adherence to a patient-focused, multidisciplinary, and multimodal approach. Alleviating the injury and stress caused by surgery or disease is the core principle of ERAS, which has been shown to reduce complication rates after surgery, promote patient recovery, decrease hospital length of stay and reduce costs. ERAS has been widely applied in many surgical perioperative fields, and it has achieved remarkable effects. However, there are few applications of ERAS in neurosurgery, especially in clinical trials of neurocritical care patients. Therefore, the investigators attempt to conduct the study of ERAS in neurosurgical intensive patients using a series of optimized perioperative managements that have been verified to be effective by evidence-based medicine, and to evaluate the safety and effectiveness of ERAS in neurocritical care. The aim of this study is to explore the most suitable ERAS protocols to accelerate the postoperative rehabilitation process of neurocritical care patients, and to provide more evidence-based medicine for the effectiveness and safety of ERAS in neurosurgery.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating an "Enhanced Recovery After Surgery" (ERAS) protocol adapted for patients in neurocritical care — specifically those with moderate to severe traumatic brain injury or serious brain or blood vessel events requiring intensive neurosurgical care. ERAS protocols use evidence-based steps to speed up recovery and reduce complications. **You may be eligible if...** - You are between 18 and 75 years old - You have a moderate or severe traumatic brain injury or a serious cerebrovascular condition requiring neurosurgical intensive care - Your hospital stay is expected to be at least one week - Your guardian or legal representative is able to provide informed consent **You may NOT be eligible if...** - You are receiving non-surgical treatment only - You were declared brain dead within 24 hours of admission - You are on dialysis, have end-stage cancer, or have widespread cancer - You withdrew from treatment during hospitalization or were discharged early - You required an unplanned second surgery during the study period Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREEnhanced recovery after surgery

The technologies, processes and measures of enhanced recovery after surgery focus on the following aspects: 1. Early assessment and treatment 2. Optimized anesthetic protocol 3. Reducing surgical stress 4. Multi-modal comprehensive monitoring 5. Comprehensive diagnosis and treatment in neurosurgical intensive care 6. Intensive early rehabilitation treatment

PROCEDUREConventional therapy

Conventional therapy in neurocritical care.


Locations(1)

Shanghai 6th People's Hospital

Shanghai, China

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NCT06241482


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