Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

This trial is comparing two different two-drug combination therapy approaches as a starting treatment for people newly diagnosed with type 2 diabetes. It aims to find out which combination approach is better at controlling blood sugar long-term while minimizing side effects. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with type 2 diabetes within the past 5 years - You are either untreated or only taking metformin - Your HbA1c (a measure of blood sugar over 3 months) is above 6.5% - Your weight has been stable for the past 3 months - You are in generally good health **You may NOT be eligible if...** - You have type 1 diabetes (positive anti-GAD antibodies) - You are pregnant or planning to become pregnant - You have advanced diabetic eye disease (proliferative retinopathy) - You have significant kidney problems (high creatinine) - You are already on multiple diabetes medications beyond metformin Talk to your doctor to see if this trial is right for you.