RecruitingNot ApplicableNCT06251297

Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer

Sponsor

University Hospital, Toulouse

Enrollment

40 participants

Start Date

Apr 29, 2024

Study Type

INTERVENTIONAL

Conditions

Colorectal, Cancer

Summary

The management of colorectal cancer often requires oxaliplatin-based chemotherapy, either as part of curative treatment plans or exclusively in palliative situations. Oxaliplatin therefore plays a key role in the management of colorectal cancer. In addition to its digestive and hematological toxicity, oxaliplatin frequently induces chronic, often limiting, sensitive peripheral neuropathy. Only early discontinuation of oxaliplatin can limit the risk of clinically limiting neurotoxicity (grade ≥ 3). In oncology, managing the side-effects of treatment is an essential objective of supportive care, and is open to a variety of complementary medicines, including reflexology. This technique, derived from traditional Chinese medicine, involves stimulating reflex points on the arch of the foot.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study explores whether foot reflexology — a massage technique applying pressure to specific areas of the feet — can prevent or reduce nerve damage (neuropathy) in the hands and feet caused by a chemotherapy drug called oxaliplatin, which is commonly used for colorectal cancer. **You may be eligible if...** - You are over 18 years old - You are being treated for colorectal cancer with intravenous oxaliplatin chemotherapy - You are able to complete self-reported questionnaires - Your expected survival is at least 12 weeks **You may NOT be eligible if...** - You already have nerve damage in your hands or feet before starting chemotherapy - You have received reflexology in the past 6 months - You have blood clots, open wounds, foot trauma, or foot metastases that would make foot reflexology unsafe - You are covered by a legal protection order Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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