RecruitingNot ApplicableNCT06251700

Longterm Effectiveness of Artificial Intelligence-assisted Colonoscopy on Adenoma Recurrence

Longterm Effectiveness of Artificial Intelligence-assisted Colonoscopy on Adenoma Recurrence - a Prospective Longitudinal Follow-up of Randomized Controlled Trial


Sponsor

Chinese University of Hong Kong

Enrollment

775 participants

Start Date

Jan 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

We hypothesize that AI-assisted colonoscopy can reduce post-colonoscopy neoplasia incidence after 3 years, over standard colonoscopy. Moreover, this protective effect may allow surveillance intervals to be lengthened, by modifying long-term outcome of high-risk subgroup.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Subjects are eligible if:
  • (i) They underwent randomization to receive colonoscopy with/without CADe in ENDOAID-TRAIN study \[NCT04838951\]; (ii) They are fit and willing to undergo surveillance colonoscopy at year 3; (iii) Written informed consent obtained.

Exclusion Criteria2

  • Subjects will be excluded from the study if they have any of the followings:
  • (i) Incomplete colonoscopy during index procedure; (ii) Known residual colorectal neoplasia not removed (except hyperplastic polyps); (iii) Underwent unscheduled interval colonoscopy before year 3; (iv) Contraindications to surveillance colonoscopy at year 3; (v) Advanced comorbid (American Society of Anesthesiologists grade 4 or above); (vi) History of CRC, hereditary polyposis syndrome or inflammatory bowel disease; (vii) History of colectomy at any time point.

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Interventions

DEVICEENDO-AID CADe

ENDO-AID CADe will be used during the withdrawal process of the colonscopy


Locations(1)

Prince of Wales Hospital

Hong Kong, Hong Kong

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NCT06251700


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