RecruitingNCT06252922

Diet-Induced Changes in GEnetic Material

A Pilot Study to Examine Metabolic Flexibility as a Mechanism for Diet- Induced Epigenetic Alterations in Male Gametes

Sponsor

Pennington Biomedical Research Center

Enrollment

10 participants

Start Date

Nov 11, 2023

Study Type

OBSERVATIONAL

Conditions

Metabolic Disturbance Diet, Healthy Body Weight

Summary

This is a pilot study in 10 men to test the hypothesis that perturbations in substrate flux and the circulating metabolic and pro-inflammatory milieus during a high-fat diet paradigm will modulate DNA methylation of genes in sperm associated with obesity and cardiometabolic dysfunction.

Eligibility

Sex: MALEMin Age: 20 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with body weight, diet, healthy, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include men aged 20 Years to 35 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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