Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients
The Methodist Hospital Research Institute
1,000 participants
Dec 8, 2020
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to investigate how bacterial populations from the intestine and mouth of patients change during the hospitalization period and evaluate if some populations of specific bacteria increase or decrease the risk of acquiring an infection or becoming colonized by pathogenic bacteria. Participants will have the following samples collected during enrollment: stool samples (maximum 2x/week), blood draws (1x/week), oral swab (1x/week).
Eligibility
Inclusion Criteria1
- Admission to an intensive care unit or stem cell transplant unit (for allogeneic stem cell transplantation) within previous 24 hours
Exclusion Criteria4
- \<18 years of age
- Pregnancy
- History of inflammatory bowel disease (Crohn's disease, ulcerative colitis)
- Gastrointestinal derivation (colostomy, ileostomy, etc.)
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Locations(2)
View Full Details on ClinicalTrials.gov
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NCT06258551