RecruitingNot ApplicableNCT06259279

High Impact Training to Patients with Prostate Cancer and Bone Metastases


Sponsor

Copenhagen University Hospital at Herlev

Enrollment

102 participants

Start Date

Feb 6, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

HIP is a randomized controlled trial. The aim is investigate the effect, safety and feasibility of brief, high-impact exercise targeting bones in patients with prostate cancer and bone metastases. Furthermore, to investigate the effects of the intervention on bone status (bone mineral density) and body composition, physical function and performance, patient reported quality-of-life outcomes, falls and hospitalizations. The effects of resistance training on the antitumor immunity will be assessed in the peripheral blood and tumor biopsies (HIPimmune).


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study, called the HIP trial, is testing whether high-impact exercise training (like jumping and weight-bearing activities) is safe and beneficial for men with prostate cancer that has spread to the bones and is being treated with hormone therapy. **You may be eligible if...** - You have prostate cancer that has spread to the bones (metastatic hormone-sensitive prostate cancer) - You started hormone-blocking treatment (androgen deprivation therapy) less than 12 months ago - You are in good enough health to exercise (ECOG score below 2) - You can walk without a walking aid - You can read and understand Danish **You may NOT be eligible if...** - You have a physical condition that prevents exercise - You have heart, muscle, bone, or nerve problems that make exercising unsafe - You need opioid pain medication for bone pain - You are planning to have, or have had, palliative radiation to the bones - You had major surgery in the past 6 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALHigh intensity high impact exercise intervention

Patients in the intervention group will receive a 32-week exercise-based intervention that includes: \- Supervised and group-based exercise training in the hospital, twice a week. Each session lasts approximately 30 minutes.


Locations(1)

Herlev and Gentofte Hospital

Herlev, Herlev, Denmark

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06259279


Related Trials