RecruitingPhase 1NCT06260514

Study of APR-1051 in Patients With Advanced Solid Tumors

A Phase 1, Open-Label, Multicenter, First-In-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of APR-1051 in Patients With Advanced Solid Tumors


Sponsor

Aprea Therapeutics

Enrollment

90 participants

Start Date

Jun 13, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess the safety and effectiveness of APR-1051 through the performance of a Phase 1, open-label, safety, PK, and preliminary efficacy study of oral APR-1051 in patients with advanced solid tumors.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called APR-1051 for people with advanced solid tumor. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAPR-1051

WEE1 Inhibitor


Locations(6)

University Hospitals, Cleveland Medical Center

Cleveland, Ohio, United States

MD Anderson Cancer Center (MDACC)

Houston, Texas, United States

NEXT Oncology- Houston

Houston, Texas, United States

NEXT Oncology -Dallas

Irving, Texas, United States

NEXT Oncology -San Antonio

San Antonio, Texas, United States

NEXT Oncology -Virginia

Fairfax, Virginia, United States

View Full Details on ClinicalTrials.gov

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NCT06260514


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