RecruitingNCT06263530

Prognostic Significance of ctDNA in HL

Prognostic Significance of Circulating Tumor DNA in Hodgkin Lymphoma


Sponsor

Interni hematologicka klinika FNKV

Enrollment

500 participants

Start Date

Jan 2, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Specific somatic mutations using ctDNA will be analyzed in predefined subgroups of cHL (e.g., age \<60 and ≥ 60 years, EBV). These mutations will be correlated with response to the treatment in the first line, in the relapse, during brentuximab vedotin and/or nivolumab treatment. Circulating tumor DNA will be correlated with the extent of tumor mass and chemo/radiotherapy.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Patients ≥ 18 years with newly histologically confirmed classical Hodgkin lymphoma (cHL) will be enrolled
  • signing the informed consent

Exclusion Criteria1

  • Pacients without signing the informed consent

Locations(5)

University Hospital Hradec Kralove

Hradec Králové, Czechia

University Hospital Olomouc

Olomouc, Czechia

University Hospital Kralovske Vinohrady

Prague, Czechia

Charles University

Prague, Czechia

General University Hospital

Prague, Czechia

View Full Details on ClinicalTrials.gov

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NCT06263530


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