RecruitingNot ApplicableNCT06263829

HCV Tappt Adherence Study

Effectiveness of a Novel Smart Tag Technology in a Pharmacy-Led Setting to Improve Adherence, Patient-Centered Care and Outcomes in HCV


Sponsor

University of Illinois at Chicago

Enrollment

30 participants

Start Date

Jun 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this non-inferiority clinical trial is to evaluate the efficacy of Tappt, a novel digital medication companion solution, among individuals with hepatitis C virus (HCV) who are starting a daily oral medication regimen following standard of care in a clinical pharmacy setting. * The primary aim is to assess the non-inferiority of Tappt with medication adherence, treatment completion, sustained virologic response (SVR) assessment, and SVR achievement rates. * The secondary aim is to assess the efficacy of Tappt at enabling pharmacists to personalize treatment and management decision based on participants' reported barriers to adherence, care, and SVR achievement. Participants will download and utilize the Tappt app to record adherence to oral medication. For the purposes of this study, adherence for participants in the intervention arm will be measured using a modified medication possession ratio (MPR) measure called medication tag scan ratio (MTSR). MTSR is defined as a percentage of the number of times participants scanned their passive tags versus the total of expected tag scans based on that participant's medication regimen and treatment period. Upon study completion, a retrospective matched control will be established for the intervention group. Historic data for the matched control's adherence, treatment completion, SVR assessment, and SVR rates will be compared to the intervention arm.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a smartphone app designed to help people with hepatitis C stay on track with their oral antiviral medications and complete their full course of treatment. **You may be eligible if...** - You are 18 or older - You have been diagnosed with hepatitis C (confirmed by a blood test) - You are starting one of two specific oral hepatitis C treatments (glecaprevir/pibrentasvir or sofosbuvir/velpatasvir) - Your medication is being managed by a pharmacist at UI Health - You have a smartphone (iPhone 7 or newer, or Android 2012 or newer) with reliable internet access - You speak and read English **You may NOT be eligible if...** - You cannot read or speak English - You are pregnant - You have severe liver disease (advanced cirrhosis or liver cancer) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERUse of Tappt App

Use of Tappt, a novel digital medication companion solution


Locations(1)

UIH

Chicago, Illinois, United States

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NCT06263829


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