RecruitingPhase 3NCT06267118

Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis

A Randomized Controlled Trial on the Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis in Children


Sponsor

Combined Military Hospital, Pakistan

Enrollment

60 participants

Start Date

Nov 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare the efficacy of hypertonic saline nebulization with adrenaline nebulization in the treatment of acute bronchiolitis in children. Main aim is to evaluate the following in both group of patients 1. Improvement in Wood-Downes clinical score (WDF score) in bronchiolitis 2. Length of Hospitalization


Eligibility

Min Age: 1 MonthMax Age: 2 Years

Inclusion Criteria1

  • All children admitted in PICU with acute bronchiolitis

Exclusion Criteria6

  • children with co-exiting illnesses like
  • Congenital Heart Disease
  • Immunodeficiency
  • other Infectious disease like Meningitis, encephalitis, Pneumonia, TORCH
  • Kidneys or liver problem
  • Seizures

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Interventions

DRUGHypertonic Saline Solution, 1 Ml

Dilute 0.3 ml hypertonic saline with 3 ml normal saline for nebulization

DRUGAdrenaline

dilute 0.3 ml adrenaline with 3 ml normal saline for nebulization


Locations(1)

Combined Military Hospital

Nowshera, KPK, Pakistan

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NCT06267118