RecruitingNCT06267378

Assessing Frailty and Its Impacts on Patients Facing Major GI Surgery

Assessing Frailty and Its Impacts in Older Patients Facing Major Gastrointestinal Surgery


Sponsor

Doncaster And Bassetlaw Hospitals NHS Foundation Trust

Enrollment

100 participants

Start Date

Aug 30, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The study team will look at 3 new tests that will make it easier to measure frailty in patients awaiting surgery for cancer and compare them against standard clinical measures of frailty in a pilot study. The expected outcome is that evidence will be collated in order to apply for a major grant to look at improving the care of frail patients with cancer in the future.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Male or female.
  • Aged 70 years and over.
  • Patients with a diagnosis of primary operable colorectal cancer where treatment includes a planned curative surgical procedure.
  • About to undergo elective surgery for cancer.
  • Mental capacity to consent.

Exclusion Criteria3

  • Patients with unresectable cancer.
  • Patients presenting as an emergency.
  • Patients who are having chemotherapy or radiotherapy before their surgery.

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Interventions

OTHERFrailty measure

All participants will be asked to complete baseline assessments and a blood test. 30 participants out of the 100 will be selected to wear a digital motion device before their surgery for seven days. (15 participants will be non-frail and 15 patients will be frail). Where possible, all baseline assessments will be scheduled to coincide with a routine clinic/hospital visit. The first assessment will complete functional, frailty, nutritional, and quality of life questionnaires. A blood test will be taken for baseline tests and metabolomic assessment. Participants who opt into having a digital motion device will also be shown how to use the device and will wear this for seven days. Written instructions to fit the device will also be given.


Locations(1)

Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust

Doncaster, South Yorkshire, United Kingdom

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NCT06267378


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