Effects of a Combined Exercise Intervention on the Gut Microbiome of People With Type 2 Diabetes
Understanding the GUT Microbiome Through a Fitness Intervention of Aerobic and Resistance Training for Individuals With Type 2 Diabetes Mellitus (GUTFIT Study)
University of New Brunswick
40 participants
Feb 29, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this experimental trial is to learn about the changes in bacterial diversity in individuals with type 2 diabetes who perform endurance and strength training at different intensities. Participants with type 2 diabetes will be randomly assigned to 16 weeks of either moderate-intensity endurance and strength training or high-intensity endurance and strength training. Researchers will compare the moderate-intensity and high-intensity exercise groups for differences in glycemia and bacterial diversity.
Eligibility
Inclusion Criteria6
- Adults aged 19 - 64 years old;
- Diagnosed with type 2 diabetes;
- An HbA1c \>= 7.0%;
- Not currently meeting the recommended levels of physical activity for optimal health (i.e., 150 minutes of moderate-to-vigorous physical activity and 2+ days/week of resistance training);
- Average less than 10,000 steps per day over the last seven days;
- No change in diabetes medications over the last three months.
Exclusion Criteria8
- Not diagnosed with type 2 diabetes;
- Partaking in a self-reported regular exercise regimen, defined as consistent participation in running or jogging activity, attending exercise classes every week, or averaging 10,000 steps per day or more over seven days;
- Currently performing two days of resistance training per week;
- Having an injury that would prevent safe participation in the intervention;
- A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions;
- A diagnosis of any red blood cell altering condition (i.e., sickle cell anemia, poikilocytosis);
- Currently living with any cardiovascular disease which would impact the ability to participate in exercise safely;
- Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity.
Interventions
High intensity exercise
Moderate intensity exercise
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06268743