RecruitingNot ApplicableNCT06280079

Ultra-high-caloric, Fatty Diet in ALS

Efficacy, Safety, and Tolerability of Ultra-high-caloric, Fatty Diet (UFD) in Amyotrophic Lateral Sclerosis (ALS)

Sponsor

University of Ulm

Enrollment

392 participants

Start Date

Jun 1, 2024

Study Type

INTERVENTIONAL

Conditions

Amyotrophic Lateral Sclerosis

Summary

This study aims at evaluating efficacy and tolerability of an ultra-high-caloric, fatty diet (UFD) compared to placebo in patients with amyotrophic lateral sclerosis (ALS).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Placebo and Ultra-high-caloric fatty diet for people with amyotrophic lateral sclerosis. The study is currently recruiting participants at 23 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTUltra-high-caloric fatty diet

100% fat (70g), saturated fatty acids 7,5g, monounsaturated fatty acids 42,6g, polyunsaturated fatty acids 19,9g, long-chain fatty acids 100%, ratio omega-6 to omega-3 fatty acids 5:1, protein 0g, carbohydrates 0g, fiber 0g

OTHERPlacebo

\<5% fat (\<3,5g), protein 0g, carbohydrates 0g, fiber 0g

Locations(23)

RWTH Aachen

Aachen, Germany

Charité Universitätsmedizin Berlin

Berlin, Germany

University Clinic Bochum

Bochum, Germany

University Clinic Bonn

Bonn, Germany

Technical University Dresden

Dresden, Germany

University Clinic Erlangen

Erlangen, Germany

Alfried Krupp Krankenhaus Essen

Essen, Germany

University Clinic Göttingen

Göttingen, Germany

University Clinic Halle

Halle, Germany

Hannover Medical School

Hanover, Germany

University Clinic Jena

Jena, Germany

DRK Clinic Kassel

Kassel, Germany

Klinikum Kempten

Kempten, Germany

University Clinic Leipzig

Leipzig, Germany

University Clinic Lübeck

Lübeck, Germany

Diakonissenkrankenhaus Mannheim

Mannheim, Germany

Technical University Munich

Munich, Germany

University Clinic Münster

Münster, Germany

University Clinic Regensburg

Regensburg, Germany

University Clinic Rostock

Rostock, Germany

University of Ulm

Ulm, Germany

DKD HELIOS Clinic Wiesbaden

Wiesbaden, Germany

University Clinic Würzburg

Würzburg, Germany

View Full Details on ClinicalTrials.gov

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NCT06280079

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