Early Transcatheter Mitral Valve Repair After Myocardial Infarction
Fundación para la Investigación Biosanitaria del Principado de Asturias
250 participants
Dec 24, 2024
INTERVENTIONAL
Conditions
Summary
To explore the impact of early transcatheter edge-to-edge repair of acute functional mitral regurgitation after myocardial infarction on the combined incidence of death and heart-failure associated hospitalisations at one-year follow-up, and quality of life and LV remodelling at two-year follow-up.
Eligibility
Inclusion Criteria3
- Patients with symptomatic moderate to severe or severe MR after acute MI
- Age > 18 years
- Based on the following classification recently published in "Transcatheter Mitral Edge-to-Edge Repair for Treatment of Acute Mitral Regurgitation" by M. Shuvy et al. (Can J Cardiol. 2023) patients will be included if categorized in Type 2, 3 or 4:
Exclusion Criteria4
- Primary MR (e.g. papillary muscle rupture)
- EF ≤ 25%
- Accepted for CABG
- Presence of cardiogenic shock (AMR type 1)
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Interventions
TEER will be planned and performed as soon as possible, but within 60 days after index myocardial infarction, and within 30 days of randomisation using the MitraClip device.
MitraClip
Optimal medical treatment
Locations(32)
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NCT06282042